Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820314 | 0.75 | CHRNA7 (0.37) | CHRNA7PIK3CAMTORNPC1ALOX5AP | |
| SCHEMBL2604908 | 0.74 | ESR1 (0.42) | CHRNA7ESR1ESR2PRMT5WDR77 | |
| SCHEMBL24838544 | 0.72 | ESR1 (0.36) | CHRNA7ESR1ESR2PRMT5WDR77 | |
| SCHEMBL13467095 | 0.72 | LMNA (0.35) | CHRNA7ESR1ESR2PRMT5WDR77 | |
| SCHEMBL14241223 | 0.72 | ESR1 (0.49) | CHRNA7ESR1ESR2PRMT5WDR77 | |
| SCHEMBL15831685 | 0.72 | ESR1 (0.41) | CHRNA7ESR1ESR2PRMT5WDR77 | |
| SCHEMBL5102670 | 0.72 | ESR1 (0.44) | ESR1ESR2PRMT5WDR77PIK3CA | |
| SCHEMBL20802535 | 0.72 | ESR1 (0.41) | CHRNA7ESR1ESR2PRMT5WDR77 | |
| SCHEMBL4369960 | 0.72 | ESR1 (0.41) | CHRNA7ESR1ESR2PRMT5WDR77 | |
| SCHEMBL19106116 | 0.72 | IDO1 (0.44) | NPC1RAB9ACNR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | CHRNA7 4724/4885ESR1 1847/4885ESR2 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.