SCHEMBL25825682

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL305498	0.92	TAAR1 (1.00)	TAAR1CASP3SENP7MDM2SMN1; SMN2
	SCHEMBL23999548	0.92	MDM2 (0.83)	TAAR1CASP3SENP7MDM2SMN1; SMN2
	SCHEMBL12010916	0.88	CASP3 (1.00)	TAAR1CASP3SENP7SMN1; SMN2TP53
	SCHEMBL9479905	0.88	CASP3 (1.00)	TAAR1CASP3SENP7SMN1; SMN2TP53
	SCHEMBL30051986	0.88	CASP3 (1.00)	TAAR1CASP3SENP7SMN1; SMN2TP53
	SCHEMBL24003958	0.88	KMT2A (0.67)	TAAR1CASP3SENP7MDM2SMN1; SMN2
	SCHEMBL31668740	0.86	MDM2 (0.95)	TAAR1MDM2SMN1; SMN2EPHX1KMT2A
	SCHEMBL23069097	0.85	TAAR1 (0.85)	TAAR1CASP3SENP7MDM2SMN1; SMN2
	SCHEMBL10020286	0.84	MDM2 (1.00)	TAAR1MDM2SMN1; SMN2EPHX1KMT2A
	SCHEMBL29393952	0.82	JAK2 (0.86)	SMN1; SMN2EPHX1KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.