SCHEMBL25825776

SCHEMBL25825776

CC(C)(C)C(=O)OCOP(=O)(OCOC(=O)C(C)(C)C)Oc1ccc(I)cc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
BTN3A1 O00481 8/20 0.41
ELANE P08246 3/20 0.37
ENO1 P06733 1/20 0.36
TRPV1 Q8NER1 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10379906 0.85 ALDH1A1 (0.50) ALDH1A1BTN3A1ELANEENO1
SCHEMBL16069998 0.79 ALDH1A1 (0.45) ALDH1A1BTN3A1ELANEENO1
SCHEMBL16069996 0.79 ALDH1A1 (0.45) ALDH1A1BTN3A1ELANEENO1
SCHEMBL16069997 0.79 ALDH1A1 (0.45) ALDH1A1BTN3A1ELANEENO1
SCHEMBL10378800 0.76 BTN3A1 (0.50) ALDH1A1BTN3A1ELANEENO1CYP3A4
SCHEMBL20710737 0.73 CA2 (0.60) ALDH1A1CA1CA2BCHEACHE
SCHEMBL13141363 0.71 BTN3A1 (0.46) ALDH1A1BTN3A1ENO1
SCHEMBL14274522 0.70 CA1 (0.45) ALDH1A1CA1CA2
SCHEMBL6551411 0.70 CYP3A4 (0.58) ALDH1A1CA1CA2BCHEACHE
SCHEMBL28016471 0.70 TSHR (0.50) ALDH1A1BTN3A1ENO1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131333-A1 BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF 中国科学院上海药物研究所 2023-07-13 WO disclosed