SCHEMBL25825806

SCHEMBL25825806

c1ccc2sc(-c3c4ccccc4c(-c4cc5ccccc5c5ccccc45)c4ccccc34)cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.56
NQO2 P16083 1/20 0.56
APP P05067 2/20 0.44
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
ALDH1A1 P00352 2/20 0.37
HIF1A Q16665 2/20 0.37
HSD17B10 Q99714 2/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13978933 0.88 NQO1 (0.57) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL13979021 0.86 NQO1 (0.55) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL13979064 0.86 NQO1 (0.55) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL28113158 0.86 NQO1 (0.54) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL12115251 0.82 NQO1 (0.58) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL18858091 0.82 NQO1 (0.63) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL2966644 0.80 ALDH1A1 (0.52) NQO1ALDH1A1HIF1AHSD17B10HPGD
SCHEMBL19678607 0.79 NQO1 (0.55) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL19497669 0.77 NQO1 (0.51) NQO1NQO2APPHSD17B1HSD17B2
SCHEMBL18858104 0.77 NQO1 (0.49) NQO1NQO2APPHSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132488-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-07-13 WO disclosed