SCHEMBL2966644

SCHEMBL2966644

c1ccc2c(c1)cc(-c1c3ccccc3c(-c3cc4ccccc4c4ccccc34)c3ccccc13)c1ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HSD17B10 Q99714 4/20 0.52
HIF1A Q16665 3/20 0.52
CYP1B1 Q16678 1/20 0.52
TRPM4 Q8TD43 1/20 0.52
HPGD P15428 3/20 0.52
TSHR P16473 2/20 0.52
MAPK1 P28482 2/20 0.52
CASP1 P29466 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HPRT1 P00492 3/20 0.50
CYP11B1 P15538 1/20 0.48
CYP2A6 P11509 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
NISCH Q9Y2I1 1/20 0.46
SOS1 Q07889 1/20 0.44
CYP1A2 P05177 3/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1527438 0.92 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL19181278 0.89 CYP11B1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL1527576 0.89 ALDH1A1 (0.53) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL15763546 0.89 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL7905250 0.86 ALDH1A1 (0.60) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL29637136 0.86 ALDH1A1 (0.60) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL18754922 0.85 TRPM4 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL25956797 0.85 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL19058882 0.85 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4
SCHEMBL12263024 0.84 CYP11B1 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1TRPM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 ALDH1A1 944/4885HSD17B10 1895/4885HIF1A 3067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.