Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825838 | 0.83 | ESR2 (0.35) | HDAC1ESR2NR1H2NAMPTMIF | |
| SCHEMBL25825899 | 0.81 | ESR2 (0.49) | HDAC1ESR2NR1H2DDB1CRBN | |
| SCHEMBL25604140 | 0.81 | HDAC1 (0.45) | HDAC1ESR2NR1H2DDB1CRBN | |
| SCHEMBL15893739 | 0.78 | ESR2 (0.51) | HDAC1ESR2NR1H2DDB1CRBN | |
| SCHEMBL16269644 | 0.75 | DDB1 (0.45) | HDAC1ESR2NR1H2DDB1CRBN | |
| SCHEMBL21496681 | 0.74 | DDB1 (0.48) | ESR2DDB1CRBNNAMPTMAPK1 | |
| SCHEMBL15896377 | 0.73 | ESR2 (0.49) | HDAC1ESR2NR1H2DDB1CRBN | |
| SCHEMBL21805005 | 0.73 | DDB1 (0.47) | HDAC1ESR2NR1H2DDB1CRBN | |
| SCHEMBL12682903 | 0.72 | ADORA1 (0.53) | ESR2NR1H2MAPK1ADORA1KMT2A | |
| SCHEMBL15503203 | 0.71 | ESR2 (0.56) | HDAC1ESR2NR1H2NAMPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |