Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25604196 | 0.88 | ESR2 (0.58) | ESR2NR1H2DDB1CRBNHDAC1 | |
| SCHEMBL25604259 | 0.88 | ESR2 (0.58) | ESR2NR1H2DDB1CRBNHDAC1 | |
| SCHEMBL15893739 | 0.83 | ESR2 (0.51) | ESR2NR1H2DDB1CRBNHDAC1 | |
| SCHEMBL25604351 | 0.82 | ESR2 (0.53) | ESR2NR1H2MAPK1GPR119POLB | |
| SCHEMBL15896377 | 0.81 | ESR2 (0.49) | ESR2NR1H2DDB1CRBNHDAC1 | |
| SCHEMBL25825900 | 0.81 | HDAC1 (0.43) | ESR2NR1H2DDB1CRBNHDAC1 | |
| SCHEMBL25825837 | 0.80 | ESR2 (0.40) | ESR2NR1H2DDB1CRBNHDAC1 | |
| SCHEMBL25825898 | 0.78 | ESR1 (0.45) | ESR2MAPK1 | |
| SCHEMBL28242061 | 0.78 | NR1H2 (0.43) | ESR2NR1H2DDB1CRBNHDAC1 | |
| SCHEMBL24761586 | 0.77 | ESR2 (0.50) | ESR2NR1H2DDB1CRBNHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |