Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | GPR183 | P32249 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825900 | 0.83 | HDAC1 (0.43) | ESR2L3MBTL1HDAC1MIFLMNA | |
| SCHEMBL25825837 | 0.82 | ESR2 (0.40) | ESR2HDAC1GPR183JAK2JAK1 | |
| SCHEMBL25825841 | 0.74 | L3MBTL1 (0.37) | L3MBTL1CYP1A2CYP3A4GRM5JAK2 | |
| SCHEMBL29609197 | 0.71 | MAPK1 (0.50) | ESR2GPR183GPR119RORCNAMPT | |
| SCHEMBL21940889 | 0.71 | MAPK1 (0.50) | ESR2GPR183GPR119RORCNAMPT | |
| SCHEMBL25604140 | 0.70 | HDAC1 (0.45) | ESR2L3MBTL1HDAC1MIFLMNA | |
| SCHEMBL31247881 | 0.69 | EHMT2 (0.39) | L3MBTL1ALOX15ADORA1KMT2ANR1H2 | |
| SCHEMBL22317711 | 0.68 | NR1H2 (0.40) | L3MBTL1GPR119ADORA1KMT2ANAMPT | |
| SCHEMBL23051565 | 0.68 | SCD5 (0.40) | ESR2GPR183GPR119KMT2ANR1H2 | |
| SCHEMBL28989023 | 0.68 | RORC (0.40) | L3MBTL1ALOX15GPR119RORCADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |