Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20682525 | 0.83 | TDP1 (0.60) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL24434614 | 0.81 | HTR1A (0.45) | TDP1L3MBTL1CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL724866 | 0.79 | CHRNA7 (0.74) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL29485692 | 0.79 | CHRNA7 (0.74) | TDP1L3MBTL1CHRNB2CHRNA4CHRNA7 | |
| SCHEMBL9588340 | 0.78 | TDP1 (0.49) | TDP1L3MBTL1HRH3TBXAS1 | |
| SCHEMBL9589256 | 0.78 | TDP1 (0.45) | TDP1L3MBTL1TBXAS1 | |
| SCHEMBL8271491 | 0.77 | CYP2E1 (0.49) | TDP1L3MBTL1CYP1A2CYP2D6CYP2A6 | |
| SCHEMBL9588643 | 0.77 | TDP1 (0.47) | TDP1L3MBTL1TBXAS1HRH1 | |
| SCHEMBL9587577 | 0.77 | TDP1 (0.47) | TDP1L3MBTL1TBXAS1HRH1 | |
| SCHEMBL9589128 | 0.77 | TDP1 (0.47) | TDP1L3MBTL1TBXAS1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |