Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 6/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.44 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25826015 | 0.91 | DNMT1 (0.45) | MAPKAPK2DNMT1DNMT3AKDM4ERAB9A | |
| SCHEMBL30180365 | 0.90 | MAPT (0.45) | MAPKAPK2DNMT1DNMT3AKDM4ERAB9A | |
| SCHEMBL23999440 | 0.90 | MAPT (0.45) | MAPKAPK2DNMT1DNMT3AKDM4ERAB9A | |
| SCHEMBL30180369 | 0.89 | MAPT (0.45) | MAPKAPK2DNMT1DNMT3AKDM4ERAB9A | |
| SCHEMBL23999637 | 0.89 | MAPT (0.45) | MAPKAPK2DNMT1DNMT3AKDM4ERAB9A | |
| SCHEMBL30180261 | 0.88 | MAPT (0.44) | MAPKAPK2DNMT1DNMT3AKDM4ERAB9A | |
| SCHEMBL23999792 | 0.88 | MAPT (0.44) | MAPKAPK2DNMT1DNMT3AKDM4ERAB9A | |
| SCHEMBL23999438 | 0.83 | MAPT (0.49) | MAPKAPK2KDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL30180401 | 0.83 | MAPT (0.49) | MAPKAPK2KDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL23999797 | 0.83 | MAPT (0.42) | MAPKAPK2DNMT1DNMT3AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | MAPKAPK2 138/4885DNMT1 4785/4885DNMT3A 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.