Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7140069 | 0.98 | CYP1A2 (0.53) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4579136 | 0.85 | CYP1A2 (0.50) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| SCHEMBL15726347 | 0.85 | CASP2 (0.52) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| SCHEMBL12999503 | 0.84 | GAA (0.47) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| SCHEMBL7646711 | 0.83 | ALDH1A1 (0.37) | CYP1A2POLBCYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3220536 | 0.82 | GAA (0.56) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| SCHEMBL5571264 | 0.82 | KMT2A (0.52) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| SCHEMBL8576726 | 0.81 | GAA (0.49) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| SCHEMBL8530664 | 0.81 | GAA (0.49) | CYP1A2GAAPOLBCYP3A4CYP2D6 | |
| SCHEMBL4432951 | 0.81 | GAA (0.48) | CYP1A2GAAPOLBCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |