SCHEMBL25826338

SCHEMBL25826338

CC(F)(F)c1c(F)cc(CC#N)cc1C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
KIF11 P52732 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
DAO P14920 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24147884 0.88 RXRA (0.35) RXRARXRBRXRGKIF11KDM4E
SCHEMBL24147282 0.81 DAO (0.39) RXRARXRBRXRGKIF11KDM4E
SCHEMBL24147891 0.81 RXRA (0.38) RXRARXRBRXRGKIF11KDM4E
SCHEMBL25826331 0.80 RXRA (0.34) RXRARXRBRXRGKIF11KDM4E
SCHEMBL26426214 0.79 KDM4E (0.36) KDM4ETDP1
SCHEMBL25985314 0.77 RXRA (0.38) RXRARXRBRXRGKIF11KDM4E
SCHEMBL24147888 0.77 KDM4E (0.38) RXRARXRBRXRGKIF11KDM4E
SCHEMBL24369891 0.77 KDM4E (0.33) KDM4ETDP1DAO
SCHEMBL25826340 0.75 RXRA (0.37) RXRARXRBRXRGKDM4ETDP1
SCHEMBL26312453 0.75 ALDH1A1 (0.42) RXRARXRBRXRGKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240138-A1 Organic Electronic Device and Display Device Comprising the Organic Electronic Device as Well as a Composition for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-07-27 US disclosed
US-20230232711-A1 Organic Electronic Device Comprising a Compound of Formula (I), Display Device Comprising the Organic Electronic Device as Well as Compounds of Formula (I) for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-07-20 US disclosed
US-20230232712-A1 Organic Electronic Device and Display Device Comprising the Organic Electronic Device as Well as a Composition for Use in Organic Electronic Devices NOVALED GMBH (DE) 2023-07-20 US disclosed