Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.46 |
| ▸ | CDK8 | P49336 | 7/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398246 | 0.86 | IRAK4 (0.42) | IRAK4GSK3AGSK3BCCNT1CCNA2 | |
| SCHEMBL24011308 | 0.82 | CCNC (0.50) | CCNCCDK8CYP3A4 | |
| SCHEMBL12282776 | 0.79 | MAPT (0.47) | IRAK4AAK1 | |
| SCHEMBL5682821 | 0.75 | MCHR1 (0.41) | IRAK4 | |
| SCHEMBL2621791 | 0.73 | GAK (0.46) | CCNCCDK8IRAK4AAK1SLC22A12 | |
| SCHEMBL13409355 | 0.73 | IDO1 (0.50) | CCNCCDK8IRAK4AAK1IDO1 | |
| SCHEMBL12120599 | 0.73 | RPS6KA3 (0.38) | CCNCCDK8GSK3BAAK1SLC22A12 | |
| SCHEMBL4072595 | 0.72 | NOTUM (0.37) | GSK3AGSK3BCCNT1CCNA2CDK2 | |
| SCHEMBL4590870 | 0.72 | CCR1 (0.45) | IRAK4LRRK2CCNT1CCNA2CDK2 | |
| SCHEMBL25826719 | 0.71 | DOT1L (0.48) | IRAK4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
| US-20230183226-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183226-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | CCNC 821/4885CDK8 567/4885IRAK4 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.