Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24192213 | 0.75 | HTT (0.33) | — | |
| SCHEMBL22436830 | 0.74 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL25826841 | 0.72 | SMN1; SMN2 (0.31) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL25426461 | 0.72 | SMN1; SMN2 (0.36) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL21835474 | 0.71 | SMN1; SMN2 (0.38) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL22436843 | 0.69 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL22436865 | 0.68 | GAA (0.32) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL19469241 | 0.68 | IDO1 (0.39) | RAB9ANPC1MEN1KMT2A | |
| SCHEMBL23786425 | 0.67 | LMNA (0.36) | — | |
| SCHEMBL23786360 | 0.67 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133375-A1 | MACROCYCLIC COMPOUNDS AND USE AS KINASE INHIBITORS | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2023-07-13 | — | — | WO | disclosed |