Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23847679 | 0.74 | — | — | |
| SCHEMBL25827152 | 0.72 | GABRA1 (0.30) | GABRA1GABRB1GABRB2 | |
| SCHEMBL30112220 | 0.72 | BCHE (0.31) | — | |
| SCHEMBL25217000 | 0.72 | BCHE (0.31) | — | |
| SCHEMBL2016761 | 0.72 | EIF4A3 (0.35) | EIF4A3GABRA1GABRB1GABRB2 | |
| SCHEMBL17344742 | 0.71 | — | — | |
| SCHEMBL12173270 | 0.70 | EIF4A3 (0.42) | EIF4A3GABRA1GABRB1GABRB2 | |
| SCHEMBL13220718 | 0.70 | CA1 (0.39) | EIF4A3GABRA1GABRB1GABRB2 | |
| SCHEMBL20933004 | 0.70 | — | — | |
| SCHEMBL19508039 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125841-A1 | HETEROCYCLIC COMPOUND AS POLθ INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-07-06 | — | — | WO | disclosed |