Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25828854 | 0.75 | EIF4A3 (0.33) | — | |
| SCHEMBL25827151 | 0.73 | — | — | |
| SCHEMBL23691659 | 0.73 | MEN1 (0.32) | — | |
| SCHEMBL25827115 | 0.72 | EIF4A3 (0.32) | GABRA1GABRB1GABRB2 | |
| SCHEMBL20862553 | 0.72 | ANPEP (0.33) | GABRA1GABRB1 | |
| SCHEMBL30041818 | 0.72 | ATM (0.33) | — | |
| SCHEMBL23674387 | 0.72 | ATM (0.33) | — | |
| SCHEMBL26959475 | 0.71 | EIF4A3 (0.38) | GABRA1GABRB1GABRB2 | |
| SCHEMBL12533408 | 0.67 | PARP1 (0.31) | — | |
| SCHEMBL26700017 | 0.67 | PARP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125841-A1 | HETEROCYCLIC COMPOUND AS POLθ INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-07-06 | — | — | WO | disclosed |