Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12877071 | 0.88 | CES1 (0.41) | EIF4A3 | |
| SCHEMBL24253322 | 0.77 | MAOA (0.42) | — | |
| SCHEMBL25207591 | 0.77 | GABRA1 (0.48) | — | |
| SCHEMBL23674378 | 0.75 | — | — | |
| SCHEMBL25827152 | 0.75 | GABRA1 (0.30) | — | |
| SCHEMBL12173269 | 0.74 | EIF4A3 (0.41) | EIF4A3 | |
| SCHEMBL10284502 | 0.73 | DRD2 (0.33) | — | |
| SCHEMBL26700329 | 0.69 | PARP1 (0.34) | — | |
| SCHEMBL25827115 | 0.68 | EIF4A3 (0.32) | EIF4A3 | |
| SCHEMBL12604322 | 0.67 | HTR2C (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125841-A1 | HETEROCYCLIC COMPOUND AS POLθ INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2023-07-06 | — | — | WO | disclosed |