SCHEMBL258272

SCHEMBL258272

Cc1ccccc1C(Cl)Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.54
TSHR P16473 2/20 0.47
ACHE P22303 2/20 0.47
ACP3 P15309 1/20 0.41
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
GAA P10253 1/20 0.38
OPRM1 P35372 4/20 0.38
OPRD1 P41143 3/20 0.38
OPRK1 P41145 3/20 0.38
OPRL1 P41146 3/20 0.38
ALDH1A1 P00352 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP2D6 P10635 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30161744 1.00 ESR1 (0.54) ESR1TSHRACHEACP3SLC6A2
SCHEMBL11615386 0.83 ESR1 (0.54) ESR1TSHRACHEACP3SLC6A2
SCHEMBL7783992 0.81 ESR1 (0.52) ESR1TSHRACHEACP3SLC6A2
SCHEMBL38664948 0.81 ESR1 (0.52) ESR1TSHRACHEACP3SLC6A2
SCHEMBL7647280 0.80 ESR1 (0.41) ESR1TSHRACHEGAAALDH1A1
O-Xylene SCHEMBL10353038 0.79 TSHR (0.67) ESR1TSHRACHEALDH1A1CA1
SCHEMBL6351769 0.79 ESR1 (0.50) ESR1TSHRACHEACP3SLC6A2
SCHEMBL10901951 0.79 ESR1 (0.50) ESR1TSHRACHEACP3SLC6A2
SCHEMBL7380183 0.79 ESR1 (0.50) ESR1TSHRACHEACP3SLC6A2
SCHEMBL3785333 0.78 TSHR (0.50) ESR1TSHRSLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116675595-A Preparation process of phthalic dicarboxaldehyde 江西邦浦医药化工有限公司 2023-09-01 CN claimed
US-20210292551-A1 THREE-DIMENSIONAL LATTICE STRUCTURES CONTAINING OPERATING MATERIAL, COMPOSITIONS COMPRISING THE SAME, AND COMPOSITIONS AND METHODS FOR MAKING THE SAME BROWN JAMES F (US) 2021-09-23 US claimed
CN-113195675-A Thermal storage using phase change materials coated with nanoparticles 盐储能技术公司 2021-07-30 CN claimed
EP-3830162-A1 THREE-DIMENSIONAL LATTICE STRUCTURES CONTAINING OPERATING MATERIAL, COMPOSITIONS COMPRISING THE SAME, AND COMPOSITIONS AND METHODS FOR MAKING THE SAME Brown, James F. (US) 2021-06-09 EP claimed
EP-3824041-A1 HEAT STORAGE USING PHASE CHANGE MATERIAL COATED WITH NANOPARTICLES SaltX Technology AB (SE) 2021-05-26 EP claimed
CN-112566956-A Three-dimensional lattice structures comprising a working material, compositions comprising three-dimensional lattice structures, and methods and compositions for making the same 詹姆斯·F·布朗 2021-03-26 CN claimed
WO-2020127078-A1 HEAT STORAGE USING PHASE CHANGE MATERIAL COATED WITH NANOPARTICLES SALTX TECHNOLOGY AB (SE) 2020-06-25 WO claimed
WO-2020028136-A1 THREE-DIMENSIONAL LATTICE STRUCTURES CONTAINING OPERATING MATERIAL, COMPOSITIONS COMPRISING THE SAME, AND COMPOSITIONS AND METHODS FOR MAKING THE SAME BROWN JAMES F (US) 2020-02-06 WO claimed
US-10435543-B2 Rubber or elastomer compositions and processes for their manufacturing LEIBNIZ-INSTITUT FUER POLYMERFORSCHUNG DRESDEN E.V. (DE) 2019-10-08 US claimed
US-9982223-B2 Amino silicone nanoemulsion THE PROCTER & GAMBLE COMPANY (US) 2018-05-29 US claimed
EP-1664167-A4 THE POLYELECTROLYTE COMPOSITION FOR HUMIDITY SENSER, POLYELECTROLYTE INK AND PREPARATION METHOD OF POLYELECTROLYTE MEMBRANE FOR SENSOR BY INKJET PRINTING HAEUN CHEMTEC CO LTD (KR) 2006-09-20 EP claimed
EP-1664167-A1 THE POLYELECTROLYTE COMPOSITION FOR HUMIDITY SENSER, POLYELECTROLYTE INK AND PREPARATION METHOD OF POLYELECTROLYTE MEMBRANE FOR SENSOR BY INKJET PRINTING Haeun Chemtec Co. Ltd. (KR) 2006-06-07 EP claimed
CN-1252110-C Novolac aralkyl resin, its preparing method and composition containing said resin MITSUI CHEMICALS INC (JP) 2006-04-19 CN claimed
WO-2005014700-A1 THE POLYELECTROLYTE COMPOSITION FOR HUMIDITY SENSER, POLYELECTROLYTE INK AND PREPARATION METHOD OF POLYELECTROLYTE MEMBRANE FOR SENSOR BY INKJET PRINTING HAEUN CHEMTEC CO., LTD. (KR) 2005-02-17 WO claimed
EP-0362143-A2 Antistatic and electrically conductive relief images, process for manufacturing the same, coating material and radiation-sensitive polymers CIBA-GEIGY AG (CH) 1990-04-04 EP claimed
CN-88101671-A Antistatic and conduct electricity polymkeric substance and moulding material 1988-10-19 CN claimed
US-4380554-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1983-04-19 US claimed
EP-0007792-B1 SYNTHETIC POLYMERIC ADSORBENTS AND ION EXCHANGE RESINS, THEIR PRODUCTION AND PROCESSES USING THEM ROHM AND HAAS COMPANY (US) 1983-01-26 EP claimed
US-4310657-A Polymeric monohydroxybenzenoid hydroquinoid antioxidants STANDARD OIL COMPANY (INDIANA) (US) 1982-01-12 US claimed
US-4209653-A α-Olefin dimer isomerization using organo-halogens SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-06-24 US claimed