SCHEMBL3785333

SCHEMBL3785333

ClC(Cl)c1ccccc1C(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.50
CYP1A2 P05177 4/20 0.37
CYP2A6 P11509 3/20 0.37
HIF1A Q16665 3/20 0.36
LMNA P02545 3/20 0.36
CYP2C19 P33261 3/20 0.36
CYP2C9 P11712 2/20 0.36
CYP3A4 P08684 2/20 0.36
SLC6A2 P23975 2/20 0.36
HTR2B P41595 2/20 0.36
BLM P54132 2/20 0.36
KDM4E B2RXH2 1/20 0.36
NR1I2 O75469 1/20 0.36
ABCB11 O95342 1/20 0.36
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
ADRA2A P08913 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
MAPT P10636 1/20 0.36
CNR1 P21554 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28705818 0.85 GABRA1 (0.50) TSHRCYP1A2HIF1ALMNACYP3A4
SCHEMBL3911670 0.81 TSHR (0.41) TSHRCYP1A2CYP2A6HIF1ALMNA
SCHEMBL30848757 0.81 TSHR (0.50) TSHRCYP1A2CYP2A6HIF1ALMNA
SCHEMBL947512 0.81 TSHR (0.50) TSHRCYP1A2CYP2A6HIF1ALMNA
SCHEMBL258651 0.78 TSHR (0.39) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL3903006 0.78 TSHR (0.39) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL28548155 0.78 TSHR (0.39) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL9194828 0.78 TSHR (0.39) TSHRHIF1ALMNACYP2C19CYP2C9
SCHEMBL258272 0.78 ESR1 (0.54) TSHRCYP1A2CYP2A6CYP2C19CYP2C9
SCHEMBL2104519 0.78 TSHR (0.39) TSHRHIF1ALMNACYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350140-A Production process of phthalic dicarboxaldehyde 酒泉亚佳化学有限公司 2025-01-24 CN claimed
CN-116675595-A Preparation process of phthalic dicarboxaldehyde 江西邦浦医药化工有限公司 2023-09-01 CN claimed
CN-213315010-U Reaction kettle for preparing tetrachloro-o-xylene 西安思科赛实业有限公司 2021-06-01 CN claimed
CN-111825520-A Preparation process of alpha, alpha' -tetrachloro-o-xylene 西安思科赛实业有限公司 2020-10-27 CN claimed
EP-0002805-B1 PHOTOPOLYMERIZABLE COATING AND REGISTRATION MATERIALS,SUCH AS TRANSFER FOILS WITH A PHOTOSENSIBLE COATING AND PHOTORESIST MATERIALS, CONTAINING A PHOTOINITIATOR AND AN ORGANIC HALOGEN COMPOUND BASF Aktiengesellschaft (DE) 1981-01-07 EP claimed
US-4239609-A PHOTORESISTS, RELIEF IMAGES BASF AKTIENGESELLSCHAFT (DE) 1980-12-16 US claimed
US-4206152-A Process for the production of unsubstituted or polysubstituted o-phthalaldehydes CIBA-GEIGY CORPORATION (US) 1980-06-03 US claimed
EP-0003230-A2 Process for the preparation of o-phthalic aldehydes optionally having several substituents CIBA-GEIGY AG (CH) 1979-08-08 EP claimed
EP-0002805-A1 Photopolymerizable coating and registration materials,such as transfer foils with a photosensible coating and photoresist materials, containing a photoinitiator and an organic halogen compound BASF Aktiengesellschaft (DE) 1979-07-11 EP claimed
CN-223782780-U Adjustable power light source generator device for producing tetrachloro ortho-xylene 湖北相和精密化学有限公司 2026-01-09 CN disclosed
CN-223779939-U High-precision metering automatic filling machine device for producing tetrachloro ortho-xylene 湖北相和精密化学有限公司 2026-01-09 CN disclosed
CN-119350140-A Production process of phthalic dicarboxaldehyde 酒泉亚佳化学有限公司 2025-01-24 CN disclosed
CN-116675595-A Preparation process of phthalic dicarboxaldehyde 江西邦浦医药化工有限公司 2023-09-01 CN disclosed
CN-114195635-A Synthesis method of o-trifluoromethyl benzoyl chloride 江西永通科技股份有限公司 2022-03-18 CN disclosed
US-4075238-A Polyhalobenzylic disulfooxonium compounds HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1978-02-21 US disclosed
US-4056454-A FROM O-XYLENE AND CHLORINE, CARBON TETRACHLORIDE SOLVENT DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-01 US disclosed
US-4013817-A HALOGENATED AROMATIC HYDROCARBON BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-03-22 US disclosed
US-4011375-A POLYOLEFINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1977-03-08 US disclosed
US-3981936-A Method for the preparation of bis-(bromomethyl)-tetrachlorobenzenes and their use as flame-proofing agents DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-09-21 US disclosed
US-3951888-A Process for preparing polyoxyalkylene having allyl end-group KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-04-20 US disclosed