Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20545129 | 0.83 | EPHX1 (0.46) | EPHX1CACNA1HLMNADRD2TDP1 | |
| SCHEMBL18851364 | 0.83 | EPHX1 (0.46) | EPHX1CACNA1HACHEBACE1DRD2 | |
| SCHEMBL18851365 | 0.83 | EPHX1 (0.46) | EPHX1CACNA1HACHEBACE1DRD2 | |
| SCHEMBL337969 | 0.82 | EPHX1 (0.45) | EPHX1CACNA1HDRD2TDP1MEN1 | |
| SCHEMBL7131093 | 0.82 | EPHX1 (0.45) | EPHX1CACNA1HACHEBACE1DRD2 | |
| SCHEMBL22151747 | 0.82 | EPHX1 (0.45) | EPHX1CACNA1HDRD2TDP1MEN1 | |
| SCHEMBL6828378 | 0.82 | EPHX1 (0.45) | EPHX1CACNA1HACHEBACE1DRD2 | |
| SCHEMBL24951474 | 0.82 | ACHE (0.53) | EPHX1CACNA1HACHEBACE1MEN1 | |
| SCHEMBL24951714 | 0.82 | ACHE (0.53) | EPHX1CACNA1HACHEBACE1MEN1 | |
| SCHEMBL22151806 | 0.79 | ALDH1A1 (0.51) | EPHX1CACNA1HDRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129518-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |