Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3947526 | 0.84 | GAA (0.47) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL23856792 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL30253311 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL23856872 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL23857100 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL30047502 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL30047436 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EKMT2AGAAMAPT | |
| SCHEMBL7221370 | 0.79 | CA12 (0.46) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL3949856 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2AHTTGAA | |
| SCHEMBL3948889 | 0.76 | CYP11B2 (0.44) | ALDH1A1KDM4EKMT2AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |