Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827803 | 0.81 | PKN1 (0.44) | PKN1PKN2 | |
| SCHEMBL24010186 | 0.78 | MAPKAPK2 (0.44) | KITPKN1PKN2 | |
| SCHEMBL24010189 | 0.77 | LRRK2 (0.37) | KITPKN1PKN2 | |
| SCHEMBL24010183 | 0.70 | KDR (0.47) | KIT | |
| SCHEMBL24010188 | 0.69 | ABCG2 (0.41) | KIT | |
| SCHEMBL23999737 | 0.66 | F10 (0.41) | — | |
| SCHEMBL25838198 | 0.65 | TP53 (0.41) | — | |
| SCHEMBL25827001 | 0.65 | POLB (0.48) | — | |
| SCHEMBL25838529 | 0.64 | MAPK10 (0.37) | — | |
| SCHEMBL24010187 | 0.64 | MAPKAPK2 (0.43) | KITPKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | KIT 1948/4885PKN1 707/4885PKN2 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.