Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25828131 | 0.83 | PTGER4 (0.58) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL25255379 | 0.82 | KMT2A (0.57) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL22382354 | 0.81 | MAPT (0.81) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL14376796 | 0.78 | MAPT (0.61) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL1965205 | 0.77 | KMT2A (0.76) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL1305326 | 0.77 | KMT2A (0.64) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL31304627 | 0.77 | KMT2A (0.64) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL27696486 | 0.77 | MAPT (0.67) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL9043097 | 0.76 | MAPT (0.84) | MAPTALDH1A1RAB9ANPC1PKM | |
| SCHEMBL1964842 | 0.76 | MAPT (1.00) | MAPTALDH1A1RAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |