SCHEMBL25828194

SCHEMBL25828194

CC(C)(C(=O)c1ccc(OCC(=O)N(CCO)CCO)cc1OCC(=O)N(CCO)CCO)N1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.44
FKBP1A P62942 10/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
PDK2 Q15119 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
HRH3 Q9Y5N1 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
ALDH1A1 P00352 3/20 0.37
HPGD P15428 2/20 0.37
USP2 O75604 1/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828191 0.81 POLB (0.52) POLBSMN1; SMN2PDK2TRPM8NPC1
SCHEMBL25828192 0.72 POLB (0.44) POLBPDK2TRPM8NPC1RAB9A
SCHEMBL25828116 0.70 POLB (0.61) POLBSMN1; SMN2PDK2TRPM8NPC1
SCHEMBL25848418 0.69 POLB (0.48) POLBSMN1; SMN2PDK2TRPM8NPC1
SCHEMBL25848442 0.68 POLB (0.38) POLBPDK2TRPM8ALDH1A1HPGD
SCHEMBL25829502 0.68 POLB (0.61) POLBSMN1; SMN2PDK2NPC1RAB9A
SCHEMBL727286 0.67 HRH3 (0.64) POLBFKBP1ASMN1; SMN2HRH3RAB9A
SCHEMBL8176206 0.66 HRH3 (0.66) POLBSMN1; SMN2HRH3NPC1RAB9A
SCHEMBL3424748 0.66 SMN1; SMN2 (0.38) POLBSMN1; SMN2ALDH1A1USP2MAPT
SCHEMBL25828205 0.66 POLB (0.59) POLBSMN1; SMN2PDK2TRPM8NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023180075-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-28 WO disclosed
EP-4249518-A1 POLYMERIZABLE PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-09-27 EP disclosed
WO-2023126223-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-06 WO disclosed
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed