SCHEMBL25848442

SCHEMBL25848442

CCCCC(O)(CC)C(=O)c1ccc(OCC=O)cc1OCC(=O)N(CCO)CCO

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.38
PDK2 Q15119 1/20 0.36
HPGD P15428 4/20 0.33
ALDH1A1 P00352 4/20 0.33
THRA P10827 4/20 0.33
THRB P10828 4/20 0.33
CYP2D6 P10635 3/20 0.33
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TRPM8 Q7Z2W7 2/20 0.33
ALOX15 P16050 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
NR1I2 O75469 1/20 0.33
PGR P06401 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828192 0.92 POLB (0.44) POLBPDK2HPGDALDH1A1THRA
SCHEMBL25828191 0.75 POLB (0.52) POLBPDK2HPGDALDH1A1KDM4E
SCHEMBL25828194 0.68 POLB (0.44) POLBPDK2HPGDALDH1A1KDM4E
SCHEMBL25829502 0.66 POLB (0.61) POLBPDK2HPGDALDH1A1KDM4E
SCHEMBL25828116 0.65 POLB (0.61) POLBPDK2HPGDALDH1A1CYP2D6
SCHEMBL12869145 0.64 POLB (0.61) POLBALDH1A1THRATHRBTRPM8
SCHEMBL25848418 0.61 POLB (0.48) POLBPDK2HPGDALDH1A1THRB
SCHEMBL6539259 0.60 ALDH1A1 (0.50) POLBHPGDALDH1A1HSD17B10TRPM8
SCHEMBL12998150 0.59 MEN1 (0.57) POLBALDH1A1HSD17B10TRPM8MEN1
SCHEMBL25828198 0.59 THRA (0.37) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206183-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-05 EP disclosed