SCHEMBL25829502

SCHEMBL25829502

CCOc1ccc(C(=O)c2ccccc2)c(OCC(=O)N(CCO)CCO)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.61
HPGD P15428 3/20 0.49
KDM4E B2RXH2 5/20 0.48
MAPK1 P28482 2/20 0.48
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MAPT P10636 5/20 0.48
ALDH1A1 P00352 3/20 0.47
RAB9A P51151 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HCRTR1 O43613 1/20 0.47
HCRTR2 O43614 1/20 0.47
ELANE P08246 1/20 0.44
PDK2 Q15119 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALOX15 P16050 3/20 0.44
HSD17B10 Q99714 2/20 0.44
ALOX12 P18054 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828116 0.94 POLB (0.61) POLBHPGDKDM4EMAPK1LMNA
SCHEMBL25829543 0.85 POLB (0.65) POLBHPGDKDM4EMAPK1LMNA
SCHEMBL16090169 0.84 POLB (0.63) POLBHPGDKDM4EMAPK1LMNA
SCHEMBL25829494 0.81 HPGD (0.73) POLBHPGDKDM4EMAPK1LMNA
SCHEMBL2386648 0.79 POLB (0.64) POLBKDM4EMAPK1LMNAL3MBTL1
SCHEMBL25306124 0.77 HPGD (0.79) POLBHPGDKDM4EMAPK1LMNA
SCHEMBL31006408 0.77 HPGD (0.79) POLBHPGDKDM4EMAPK1LMNA
SCHEMBL7815233 0.76 LMNA (0.56) POLBHPGDKDM4EMAPK1LMNA
SCHEMBL12998150 0.76 MEN1 (0.57) POLBMAPK1LMNAL3MBTL1MAPT
SCHEMBL29091884 0.76 POLB (0.53) POLBHPGDKDM4EMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023126223-A1 POLYHYDROXYLATED PHOTOINITIATORS ARKEMA FRANCE (FR) 2023-07-06 WO disclosed