Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25748788 | 0.87 | ALDH1A1 (0.50) | ALDH1A1TDP1HTTPOLBAPEX1 | |
| SCHEMBL8023503 | 0.86 | HDAC1 (0.49) | ALDH1A1TDP1HTTPOLBAPEX1 | |
| SCHEMBL13234404 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 | |
| SCHEMBL13234389 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 | |
| SCHEMBL20996 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 | |
| SCHEMBL13234388 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 | |
| SCHEMBL13234390 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 | |
| SCHEMBL13234392 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 | |
| SCHEMBL13234425 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 | |
| SCHEMBL13234396 | 0.85 | ALDH1A1 (0.66) | ALDH1A1TDP1HTTTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100189890-A1 | HIGH ADHESION ACRYLATE COATINGS F0R A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2010-07-29 | — | — | US | claimed |
| US-7759433-B2 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-07-20 | — | — | US | claimed |
| EP-2167306-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) | 2010-03-31 | — | — | EP | claimed |
| US-20090318619-A1 | INITIATORS FOR OPTICAL COATING FORMULATIONS WITH REDUCED YELLOWNESS | ESSILOR INTERNATIONAL (FR) | 2009-12-24 | — | — | US | claimed |
| US-20080315162-A1 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (FR) | 2008-12-25 | — | — | US | claimed |
| WO-2008157607-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2008-12-24 | — | — | WO | claimed |
| EP-2167306-B1 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INT (FR) | 2013-04-17 | — | — | EP | disclosed |
| US-8048974-B2 | Initiators for optical coating formulations with reduced yellowness | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE (FR) | 2011-11-01 | — | — | US | disclosed |
| US-20100201010-A1 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-08-12 | — | — | US | disclosed |
| US-20100189890-A1 | HIGH ADHESION ACRYLATE COATINGS F0R A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2010-07-29 | — | — | US | disclosed |
| US-7759433-B2 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 2010-07-20 | — | — | US | disclosed |
| EP-2167306-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (COMPAGNIE GENERAL D'OPTIQUE) (FR) | 2010-03-31 | — | — | EP | disclosed |
| US-20090318619-A1 | INITIATORS FOR OPTICAL COATING FORMULATIONS WITH REDUCED YELLOWNESS | ESSILOR INTERNATIONAL (FR) | 2009-12-24 | — | — | US | disclosed |
| US-20080315162-A1 | High adhesion acrylate coating for a photochromic ophthalmic lens | ESSILOR INTERNATIONAL (FR) | 2008-12-25 | — | — | US | disclosed |
| WO-2008157607-A2 | HIGH ADHESION ACRYLATE COATINGS FOR A PHOTOCHROMIC OPHTHALMIC LENS | ESSILOR INTERNATIONAL (FR) | 2008-12-24 | — | — | WO | disclosed |