Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435826 | 0.88 | TDP1 (0.58) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL8020302 | 0.88 | LMNA (0.44) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL148938 | 0.88 | LMNA (0.60) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL6705875 | 0.87 | HDAC1 (0.50) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL146245 | 0.86 | POLB (0.55) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| Lithium SCHEMBL30708617 | 0.86 | LMNA (0.58) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| SCHEMBL2582827 | 0.86 | ALDH1A1 (0.49) | SMN1; SMN2MAPK1SLC6A3LMNATDP1 | |
| SCHEMBL232155 | 0.85 | POLB (0.57) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| SCHEMBL1562514 | 0.85 | POLB (0.57) | SMN1; SMN2LMNATDP1NPC1RAB9A | |
| SCHEMBL11133561 | 0.85 | ALOX5 (0.53) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034804-A1 | HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS | BAUSCH & LOMB SURGICAL, INC. (US) | 2000-06-15 | — | — | WO | disclosed |