Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633849 | 1.00 | ABCB1 (0.35) | ABCB1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL28633853 | 1.00 | ABCB1 (0.35) | ABCB1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL22154694 | 0.91 | ABCB1 (0.36) | ABCB1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL28634045 | 0.89 | ABCB1 (0.33) | ABCB1 | |
| SCHEMBL22154599 | 0.89 | ABCB1 (0.33) | ABCB1 | |
| SCHEMBL28923615 | 0.88 | ABCB1 (0.36) | ABCB1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL28923611 | 0.88 | ABCB1 (0.36) | ABCB1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL22154261 | 0.88 | ABCB1 (0.41) | ABCB1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL28642360 | 0.88 | ABCB1 (0.41) | ABCB1MEN1NPC1ALDH1A1MAPT | |
| SCHEMBL28629473 | 0.82 | FAP (0.35) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129518-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2023-07-06 | — | — | WO | disclosed |