Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4485061 | 0.82 | GSK3B (0.56) | ALDH1A1MAPTHTTCES1KDM4E | |
| SCHEMBL4047641 | 0.81 | CES2 (0.65) | ALDH1A1MAPTHTTTP53CES2 | |
| SCHEMBL1986403 | 0.78 | CES2 (0.70) | ALDH1A1MAPTHTTTP53CES2 | |
| SCHEMBL30512072 | 0.77 | CES2 (0.68) | ALDH1A1MAPTHTTTP53CES2 | |
| SCHEMBL312393 | 0.77 | CES2 (0.68) | ALDH1A1MAPTHTTTP53CES2 | |
| SCHEMBL29145573 | 0.76 | ALDH1A1 (0.59) | ALDH1A1MAPTHTTTP53CES2 | |
| SCHEMBL3765830 | 0.76 | MAPT (0.52) | ALDH1A1MAPTHTTHPGDKDM4E | |
| SCHEMBL3765733 | 0.76 | MAPT (0.56) | ALDH1A1MAPTHTTHPGDKDM4E | |
| SCHEMBL2556398 | 0.76 | CES2 (0.62) | ALDH1A1MAPTHTTTP53CES2 | |
| SCHEMBL3760982 | 0.76 | MAPT (0.52) | ALDH1A1MAPTHTTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4201928-A1 | BENZENE SULFONAMIDE THIAZOLE COMPOUNDS AND THEIR USE FOR THE TREATMENT OF CANCERS | Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) | 2023-06-28 | — | — | EP | disclosed |