SCHEMBL25829597

SCHEMBL25829597

NNC(=O)c1ccc(-c2c3cc(F)c(=O)cc-3oc3cc(O)c(F)cc23)c(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.70
USP2 O75604 6/20 0.47
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
BLM P54132 5/20 0.47
MAPT P10636 5/20 0.47
KDM4E B2RXH2 4/20 0.47
THRB P10828 4/20 0.47
RECQL P46063 4/20 0.47
TDP1 Q9NUW8 4/20 0.47
HPGD P15428 4/20 0.47
HTT P42858 3/20 0.47
CASP7 P55210 2/20 0.47
CYP3A4 P08684 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
BRCA1 P38398 1/20 0.47
CA9 Q16790 8/20 0.43
L3MBTL1 Q9Y468 5/20 0.41
POLB P06746 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14483811 0.93 FTO (0.69) FTOUSP2MEN1KMT2ABLM
SCHEMBL22434165 0.90 FTO (0.70) FTOUSP2MEN1KMT2ABLM
SCHEMBL3109289 0.90 FTO (0.78) FTOUSP2MEN1KMT2ABLM
SCHEMBL31435692 0.90 FTO (0.78) FTOUSP2MEN1KMT2ABLM
SCHEMBL18972336 0.89 FTO (0.74) FTOUSP2MEN1KMT2ABLM
SCHEMBL25829599 0.89 FTO (0.59) FTOUSP2MEN1KMT2ABLM
SCHEMBL22434201 0.88 FTO (0.67) FTOUSP2MEN1KMT2ABLM
SCHEMBL18506561 0.88 FTO (0.61) FTOUSP2MEN1KMT2ABLM
SCHEMBL10191150 0.87 FTO (0.64) FTOUSP2MEN1KMT2ABLM
SCHEMBL19731639 0.87 FTO (0.64) FTOUSP2MEN1KMT2ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4328586-A1 FLUORESCENT STAINING METHOD OSAKA UNIVERSITY (JP) 2024-02-28 EP disclosed
WO-2023132337-A1 FLUORESCENT STAINING METHOD 国立大学法人大阪大学 2023-07-13 WO disclosed