SCHEMBL31435692

SCHEMBL31435692

O=C(O)c1ccc(-c2c3cc(F)c(=O)cc-3oc3cc(O)c(F)cc23)c(C(=O)O)c1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.78
USP2 O75604 6/20 0.48
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
MAPT P10636 6/20 0.48
KDM4E B2RXH2 6/20 0.48
BLM P54132 5/20 0.48
HPGD P15428 5/20 0.48
THRB P10828 4/20 0.48
RECQL P46063 4/20 0.48
TDP1 Q9NUW8 4/20 0.48
HTT P42858 3/20 0.48
CASP7 P55210 3/20 0.48
ALOX15 P16050 2/20 0.48
CASP1 P29466 2/20 0.48
CYP3A4 P08684 1/20 0.48
BRCA1 P38398 1/20 0.48
POLB P06746 6/20 0.44
L3MBTL1 Q9Y468 5/20 0.44
GAA P10253 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3109289 1.00 FTO (0.78) FTOUSP2MEN1KMT2AMAPT
SCHEMBL18972336 0.93 FTO (0.74) FTOUSP2MEN1KMT2AMAPT
SCHEMBL21129885 0.93 FTO (0.74) FTOUSP2MEN1KMT2AMAPT
SCHEMBL12560114 0.93 FTO (0.77) FTOUSP2MEN1KMT2AMAPT
SCHEMBL17972575 0.90 FTO (0.77) FTOUSP2MEN1KMT2AMAPT
SCHEMBL25829597 0.90 FTO (0.70) FTOUSP2MEN1KMT2AMAPT
SCHEMBL22434165 0.90 FTO (0.70) FTOUSP2MEN1KMT2AMAPT
SCHEMBL24274861 0.89 FTO (0.76) FTOUSP2MEN1KMT2AMAPT
SCHEMBL10260320 0.89 FTO (0.76) FTOUSP2MEN1KMT2AMAPT
SCHEMBL22139485 0.89 FTO (0.69) FTOUSP2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070137-A Method of 百欧恩泰欧洲股份公司 2026-05-19 CN disclosed
WO-2025061863-A1 METHOD BioNTech SE (DE) 2025-03-27 WO disclosed