SCHEMBL25830578

SCHEMBL25830578

Nc1nc2cc3c(cc2[nH]1)OCCO3

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP6 P51161 2/20 0.52
PLAU P00749 1/20 0.44
HTR3E A5X5Y0 1/20 0.44
HTR3B O95264 1/20 0.44
HTR3A P46098 1/20 0.44
BACE1 P56817 1/20 0.44
HTR3D Q70Z44 1/20 0.44
HTR3C Q8WXA8 1/20 0.44
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MASP2 O00187 1/20 0.41
NUDT1 P36639 1/20 0.41
AOC3 Q16853 1/20 0.41
HDAC11 Q96DB2 1/20 0.40
GAA P10253 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11544115 0.89 FABP6 (0.52) FABP6PLAUHTR3EHTR3BHTR3A
SCHEMBL8265473 0.78 CHRNB2 (0.45) FABP6ALDH1A1MEN1KMT2AHDAC11
SCHEMBL712673 0.78 HDAC11 (0.40) ALDH1A1MEN1KMT2AHDAC11GAA
SCHEMBL15553070 0.75 FABP6 (0.49) FABP6PLAUHTR3EHTR3BHTR3A
SCHEMBL12111158 0.74 GAA (0.56) ALDH1A1MEN1KMT2AHDAC11GAA
SCHEMBL12109084 0.74 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AHDAC11GAA
SCHEMBL13542749 0.74 HSD17B10 (0.54) ALDH1A1MEN1KMT2AHDAC11GAA
SCHEMBL15799224 0.74 TDP1 (0.49) ALDH1A1MEN1KMT2AHDAC11GAA
Bromide SCHEMBL16767404 0.74 FABP6 (0.47) FABP6PLAUHTR3EHTR3BHTR3A
Hydrochloric Acid SCHEMBL27144911 0.74 RAD52 (0.50) ALDH1A1MEN1KMT2AGAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023131333-A1 BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF 中国科学院上海药物研究所 2023-07-13 WO disclosed