Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24207503 | 0.87 | NOTUM (0.41) | ALDH1A1MYCPOLBRAB9ASIRT6 | |
| SCHEMBL31312877 | 0.86 | KMT2A (0.39) | ALDH1A1MYCPOLBRAB9ASIRT6 | |
| SCHEMBL24421386 | 0.86 | KMT2A (0.39) | ALDH1A1MYCPOLBRAB9ASIRT6 | |
| SCHEMBL24319289 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MYCPOLBRAB9ASIRT6 | |
| SCHEMBL25691100 | 0.82 | ALDH1A1 (0.56) | ALDH1A1RAB9ASIRT6NPC1HTR6 | |
| SCHEMBL30525307 | 0.81 | USP30 (0.44) | ALDH1A1MYCSIRT6MEN1KMT2A | |
| SCHEMBL25634091 | 0.81 | USP30 (0.44) | ALDH1A1MYCSIRT6MEN1KMT2A | |
| SCHEMBL24207467 | 0.79 | KDM4E (0.43) | ALDH1A1POLBSIRT6HTR6MEN1 | |
| SCHEMBL27345174 | 0.79 | KDM4E (0.43) | ALDH1A1POLBSIRT6HTR6MEN1 | |
| SCHEMBL27345173 | 0.79 | KDM4E (0.43) | ALDH1A1POLBSIRT6HTR6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |