Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 6/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25301898 | 0.99 | KIF11 (0.42) | KIF11CYP11B1CYP11B2ARPGR | |
| Hydrochloric Acid SCHEMBL30510081 | 0.99 | KIF11 (0.42) | KIF11CYP11B1CYP11B2ARPGR | |
| SCHEMBL25378423 | 0.85 | CYP11B1 (0.47) | CYP11B1CYP11B2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL25255925 | 0.84 | CYP11B1 (0.46) | CYP11B1CYP11B2ALDH1A1MAPT | |
| SCHEMBL26192949 | 0.82 | AR (0.46) | CYP11B1CYP11B2ARPGRALDH1A1 | |
| SCHEMBL25378290 | 0.81 | KIF11 (0.40) | KIF11CYP11B1CYP11B2CTSSCTSK | |
| SCHEMBL30510138 | 0.81 | KIF11 (0.40) | KIF11CYP11B1CYP11B2CTSSCTSK | |
| SCHEMBL30509975 | 0.78 | KDM5A (0.39) | KIF11CYP11B1CYP11B2CTSSCTSK | |
| SCHEMBL30510102 | 0.77 | NPBWR1 (0.49) | KIF11CYP11B1CYP11B2ARPGR | |
| SCHEMBL25302186 | 0.77 | NPBWR1 (0.49) | KIF11CYP11B1CYP11B2ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122780-A9 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-11-30 | — | — | WO | disclosed |
| WO-2023122780-A2 | 2-PYRAZOLE ANILINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | THE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-06-29 | — | — | WO | disclosed |