SCHEMBL25830815

SCHEMBL25830815

C1=c2c(-c3ccc4ccccc4c3)c3ccc(-c4nccc5c4sc4ccccc45)cc3c(-c3ccc4ccccc4c3)c2=CCC1

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.40
HTR5A P47898 1/20 0.40
ALOX5 P09917 1/20 0.31
MAPKAPK2 P49137 1/20 0.31
MAPK9 P45984 2/20 0.30
MAPK10 P53779 2/20 0.30
MAPK8 P45983 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30606988 0.90 HTR2B (0.45) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL11030653 0.90 HTR2B (0.45) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL11941212 0.89 HTR2B (0.44) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL11941207 0.86 HTR2B (0.44) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL20909409 0.84 HTR2B (0.41) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL11941215 0.84 HTR2B (0.40) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL11941218 0.84 HTR2B (0.44) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL11941217 0.82 HTR2B (0.45) HTR2BHTR5AALOX5MAPKAPK2MAPK9
SCHEMBL11941211 0.82 HTR2B (0.40) HTR2BHTR5AALOX5MAPK9MAPK10
SCHEMBL11941208 0.82 HTR2B (0.38) HTR2BHTR5AALOX5MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212540-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-19 EP disclosed