Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 4/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450111 | 0.84 | GFER (0.63) | GFERCASP6ALDH1A1MAPTLMNA | |
| SCHEMBL1815274 | 0.82 | GFER (0.69) | GFERCASP6ALDH1A1MAPTLMNA | |
| SCHEMBL25831010 | 0.80 | SLC18A3 (0.47) | MGLLESR2 | |
| SCHEMBL2452376 | 0.79 | GFER (0.56) | GFERCASP6ALDH1A1MAPTLMNA | |
| SCHEMBL30985174 | 0.76 | USP2 (0.49) | GFERCASP6ALDH1A1MAPTLMNA | |
| SCHEMBL30984998 | 0.74 | GFER (0.47) | GFERCASP6ALDH1A1MAPTLMNA | |
| SCHEMBL26754753 | 0.73 | CTSB (0.30) | — | |
| SCHEMBL1047477 | 0.72 | MAPT (0.57) | GFERCASP6ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL16764224 | 0.71 | MAPT (0.57) | GFERCASP6ALDH1A1MAPTLMNA | |
| SCHEMBL3570969 | 0.70 | GFER (0.53) | GFERCASP6ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |