Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.36 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25260175 | 1.00 | CYP3A4 (0.36) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL25262771 | 0.80 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL25260300 | 0.80 | CYP3A4 (0.38) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL30524140 | 0.77 | CYP3A4 (0.41) | CYP3A4CYP2C9CYP2C19TSHRALDH1A1 | |
| SCHEMBL25424537 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL30524150 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL25306953 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL9257357 | 0.72 | TACR1 (0.43) | TSHRPOLBTACR1 | |
| SCHEMBL9264627 | 0.72 | TACR1 (0.43) | TSHRPOLBTACR1 | |
| SCHEMBL9264621 | 0.72 | TACR1 (0.43) | TSHRPOLBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154123-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V MANE FILS (FR) | 2025-05-15 | — | — | US | claimed |
| EP-4460283-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V. Mane Fils (FR) | 2024-11-13 | — | — | EP | claimed |
| CN-118742286-A | Cooling compound and composition | 玛奈·菲尔萨公司 | 2024-10-01 | — | — | CN | claimed |
| WO-2023131667-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V. MANE FILS (FR) | 2023-07-13 | — | — | WO | claimed |
| US-20250154123-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V MANE FILS (FR) | 2025-05-15 | — | — | US | disclosed |
| EP-4460283-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V. Mane Fils (FR) | 2024-11-13 | — | — | EP | disclosed |
| CN-118742286-A | Cooling compound and composition | 玛奈·菲尔萨公司 | 2024-10-01 | — | — | CN | disclosed |
| WO-2023131667-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V. MANE FILS (FR) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131667-A1 | COOLING COMPOUNDS AND COMPOSITIONS | V. MANE FILS (FR) | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154123-A1 | COOLING COMPOUNDS AND COMPOSITIONS | CBR3, DECR1, DECR2 | CYP3A4 772/4885CYP2C9 272/4885CYP2C19 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.