SCHEMBL2583117

SCHEMBL2583117

C=CC(=O)Oc1ccc(/C=C/c2ccc(OC(=O)C=C)cc2CC)c(CC)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 4/20 0.51
THRA P10827 1/20 0.40
LMNA P02545 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 2/20 0.36
TSHR P16473 1/20 0.36
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
TTR P02766 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
ALDH1A1 P00352 2/20 0.34
F2 P00734 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8835895 0.93 THRB (0.46) THRBTHRALMNAPTGS1PTGS2
SCHEMBL2579016 0.89 THRB (0.59) THRBTHRALMNAL3MBTL1HPGD
SCHEMBL2577930 0.87 THRB (0.56) THRBTHRAHPGDTSHRMEN1
SCHEMBL2583720 0.86 THRB (0.62) THRBTHRAHPGDTSHRMEN1
SCHEMBL2574997 0.84 THRB (0.60) THRBTHRAHPGDTSHRMEN1
SCHEMBL8835751 0.83 THRB (0.52) THRBTHRALMNAMAPTSMN1; SMN2
SCHEMBL27695929 0.82 THRB (0.53) THRBTHRALMNAL3MBTL1HPGD
SCHEMBL27809271 0.82 THRB (0.53) THRBTHRAHPGDTSHRMAPT
SCHEMBL8836147 0.81 THRB (0.55) THRBTHRAHPGDTSHRESR1
SCHEMBL8835770 0.81 ELANE (0.44) LMNAHPGDPTGS1PTGS2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10386681-B2 Liquid crystal display element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-08-20 US disclosed
US-20170199434-A1 LIQUID CRYSTAL DISPLAY ELEMENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-07-13 US disclosed
EP-3163367-A1 LIQUID CRYSTAL DISPLAY ELEMENT Nissan Chemical Industries, Ltd. (JP) 2017-05-03 EP disclosed
US-8049848-B2 Liquid crystal display and method of manufacturing the same and method of driving the same NEC CORPORATION (JP) 2011-11-01 US disclosed
US-20100066964-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME AND METHOD OF DRIVING THE SAME GOLD CHARM LIMITED (WS) 2010-03-18 US disclosed
US-7612848-B2 Liquid crystal display and method of manufacturing the same and method of driving the same NEC CORPORATION (JP) 2009-11-03 US disclosed
US-7561238-B2 Liquid crystal display device and method of manufacturing the same NEC LCD TECHNOLOGIES, LTD. (JP) 2009-07-14 US disclosed
US-20080074586-A1 Liquid crystal display device and method of manufacturing the same NLT TECHNOLOGIES, LTD. (JP) 2008-03-27 US disclosed
US-20070165172-A1 LIQUID CRYSTAL DISPLAY AND METHOD OF MANUFACTURING THE SAME AND METHOD OF DRIVING THE SAME GOLD CHARM LIMITED (WS) 2007-07-19 US disclosed
US-7245343-B2 Liquid crystal display device NEC LCD TECHNOLOGIES, LTD. (JP) 2007-07-17 US disclosed
US-20030025865-A1 Liquid crystal display and method of manufacturing the same and method of driving the same GOLD CHARM LIMITED (WS) 2003-02-06 US disclosed
US-6504592-B1 Liquid crystal display and method of manufacturing the same and method of driving the same NEC CORPORATION (JP) 2003-01-07 US disclosed
US-6466293-B1 Liquid crystal display with a liquid crystal orientation controlling electrode and processes for manufacturing and driving thereof NEC CORPORATION (JP) 2002-10-15 US disclosed
US-20020080320-A1 Liquid crystal display device PIXEL DISPLAY LLC 2002-06-27 US disclosed
US-20020024627-A1 Liquid crystal display device and method of manufacturing the same NEC CORPORATION (JP) 2002-02-28 US disclosed
WO-2001088605-A2 LIQUID CRYSTAL DISPLAY APPARATUS NEC CORPORATION (JP) 2001-11-22 WO disclosed
US-20010026344-A1 Liquid crystal display device and method of manufacturing the same NEC CORPORATION (JP) 2001-10-04 US disclosed
US-6256082-B1 Liquid crystal display with a liquid crystal orientation controlling electrode and processes for manufacturing and driving thereof NEC CORPORATION (JP) 2001-07-03 US disclosed
US-5959707-A Liquid crystal display having domains with different tilted-up directions as well as domains with different twist directions of lc molecules NEC CORPORATION (JP) 1999-09-28 US disclosed
US-5674576-A A LIGHT MODULATING LAYER COMPOSED OF LIQUID CRYSTAL AND HIGH POLYMER RESIN IS SANDWHICHED BETWEEN TWO SUBSTRATES HAVING ELECTRODE LAYERS, MONOMERS ARE OF(METH)ACRYLOYL COMPOUNDS WITH STIBENE OR (METH)ACRYLOYL WITH DIOXANE OR DIOXOLANES NEC CORPORATION (JP) 1997-10-07 US disclosed