Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419277 | 0.90 | THRB (0.48) | THRBHSP90AA1HSP90AB1HSD17B1MEN1 | |
| SCHEMBL13255764 | 0.88 | HGFAC (0.45) | THRBESR1ESR2HSP90AA1HSP90AB1 | |
| SCHEMBL27695929 | 0.83 | THRB (0.53) | THRBTHRAKMT2AHPGDTSHR | |
| SCHEMBL27695961 | 0.82 | THRB (0.51) | THRBESR1ESR2THRAMEN1 | |
| SCHEMBL2583117 | 0.82 | THRB (0.51) | THRBESR1ESR2THRAMEN1 | |
| SCHEMBL21170004 | 0.80 | THRB (0.47) | THRBMEN1MAPTPKMKMT2A | |
| SCHEMBL10867144 | 0.80 | ALDH1A1 (0.53) | THRBESR1ESR2MEN1MAPT | |
| SCHEMBL14451765 | 0.79 | THRB (0.36) | THRBPTPN1 | |
| SCHEMBL15495920 | 0.79 | ELANE (0.46) | THRBESR1ESR2HSP90AA1HSP90AB1 | |
| SCHEMBL18258059 | 0.78 | THRB (0.51) | THRBTHRABACE1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102040521-B | Polymerizable compound | DAINIPPON INK & CHEMICALS | 2015-04-01 | — | — | CN | disclosed |
| CN-102040521-A | Polymerizable compound | DAINIPPON INK & CHEMICALS | 2011-05-04 | — | — | CN | disclosed |
| CN-102030653-A | Polymerizable compound | DAINIPPON INK & CHEMICALS | 2011-04-27 | — | — | CN | disclosed |
| CN-101792391-A | Polymerizable biphenyl compound | DAINIPPON INK & CHEMICALS | 2010-08-04 | — | — | CN | disclosed |