Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 4/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11951247 | 0.82 | DHFR (0.55) | DHFR | |
| SCHEMBL34468030 | 0.80 | CSNK1A1 (0.61) | CSNK1A1CLK4DHFRKDM4ECHRM5 | |
| SCHEMBL15249194 | 0.75 | CSNK1A1 (0.44) | CSNK1A1CLK4DHFR | |
| SCHEMBL15250869 | 0.74 | CSNK1A1 (0.43) | CSNK1A1CLK4DHFRTLR8 | |
| SCHEMBL1143429 | 0.72 | CSNK1A1 (1.00) | CSNK1A1CLK4KDM4EMEN1GAA | |
| SCHEMBL29856493 | 0.71 | CYP2A6 (0.36) | DHFRPGK1TLR8 | |
| SCHEMBL25831452 | 0.71 | CSNK1A1 (0.54) | CSNK1A1CLK4PGK1CHRM5 | |
| SCHEMBL16074659 | 0.70 | CSNK1A1 (0.39) | CSNK1A1CLK4DHFRTLR8 | |
| SCHEMBL6363346 | 0.69 | KMT2A (0.53) | PGK1KMT2A | |
| SCHEMBL15298084 | 0.69 | CSNK1A1 (0.38) | CSNK1A1CLK4TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217201-A2 | NOVEL PYRIMIDO-HETEROCYCLIC NOVEL COMPOUND SERVING AS WEE1 INHIBITOR AND APPLICATION THEREOF | 杭州德睿智药科技有限公司 | 2023-11-16 | — | — | WO | disclosed |
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |