Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 4/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 3/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | TKT | P29401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554280 | 0.77 | PTPN1 (0.42) | CYP2A6CYP2C19CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL30731150 | 0.77 | PTPN1 (0.42) | CYP2A6CYP2C19CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL29799259 | 0.76 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL5317623 | 0.76 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL29856739 | 0.74 | — | — | |
| SCHEMBL11951247 | 0.74 | DHFR (0.55) | DHFR | |
| SCHEMBL13204736 | 0.73 | NOS3 (0.47) | CYP2A6CYP2E1CYP2B6CYP2C19CYP2C8 | |
| SCHEMBL25831727 | 0.71 | CSNK1A1 (0.56) | DHFRPGK1TLR8 | |
| SCHEMBL17362624 | 0.71 | — | — | |
| SCHEMBL29856280 | 0.70 | NOS2 (0.44) | CYP2A6CYP2E1CYP2B6CYP2C19CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169974-A1 | INHIBITORS OF URAT1 AND PHARMACEUTICAL USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2022-08-11 | — | — | WO | disclosed |