Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007604 | 0.76 | ALDH1A1 (0.58) | L3MBTL1LMNAPGRADORA3PTGS1 | |
| SCHEMBL6792877 | 0.76 | ALDH1A1 (0.58) | L3MBTL1LMNAPGRADORA3PTGS1 | |
| SCHEMBL6792870 | 0.76 | ALDH1A1 (0.58) | L3MBTL1LMNAPGRADORA3PTGS1 | |
| SCHEMBL306179 | 0.73 | POLB (0.51) | LMNAPTGS1ALDH1A1PPARGPPARA | |
| SCHEMBL24367126 | 0.73 | ALDH1A1 (0.55) | ALDH1A1KMT2ARAB9AMAPTPOLB | |
| SCHEMBL20886808 | 0.72 | PSEN1 (0.41) | PGRADORA3PTGS1SLC6A2ALDH1A1 | |
| SCHEMBL23082984 | 0.72 | ALDH1A1 (0.49) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5182481 | 0.72 | LMNA (0.56) | L3MBTL1LMNAPGRADORA3PTGS1 | |
| SCHEMBL9234482 | 0.72 | LMNA (0.56) | L3MBTL1LMNAPGRADORA3PTGS1 | |
| SCHEMBL23082878 | 0.72 | LMNA (0.57) | L3MBTL1LMNAPGRADORA3PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | L3MBTL1 3768/4885LMNA 2015/4885PGR 1139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.