Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 19/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25830256 | 0.74 | NLRP3 (0.53) | NLRP3 | |
| SCHEMBL24592584 | 0.71 | NLRP3 (0.52) | NLRP3CA2 | |
| SCHEMBL19519040 | 0.70 | NLRP3 (0.74) | NLRP3CA2 | |
| SCHEMBL26009242 | 0.70 | NLRP3 (0.48) | NLRP3CA2 | |
| SCHEMBL29804706 | 0.70 | NLRP3 (0.58) | NLRP3CA2 | |
| SCHEMBL20692216 | 0.69 | NLRP3 (0.44) | NLRP3CA2 | |
| SCHEMBL25832725 | 0.68 | CYP17A1 (0.40) | — | |
| SCHEMBL21879143 | 0.68 | NLRP3 (1.00) | NLRP3 | |
| SCHEMBL29749035 | 0.68 | GSTO1 (0.66) | NLRP3CA2 | |
| SCHEMBL19518879 | 0.68 | NLRP3 (0.48) | NLRP3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880666-B1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS AG (CH) | 2023-06-28 | — | — | EP | disclosed |