Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 11/20 | 0.33 |
| ▸ | TYMS | P04818 | 3/20 | 0.32 |
| ▸ | FPGS | Q05932 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25832449 | 0.92 | DHFR (0.33) | DHFRTYMSFPGS | |
| SCHEMBL25833360 | 0.89 | DHFR (0.32) | DHFRTYMSFPGS | |
| SCHEMBL25725532 | 0.88 | FPGS (0.32) | DHFRTYMSFPGS | |
| SCHEMBL24343468 | 0.87 | DHFR (0.33) | DHFRTYMSFPGS | |
| SCHEMBL24192579 | 0.87 | DHFR (0.44) | DHFR | |
| SCHEMBL25837523 | 0.85 | TYMS (0.32) | TYMS | |
| SCHEMBL25167229 | 0.85 | DHFR (0.32) | DHFRTYMSFPGS | |
| SCHEMBL25167230 | 0.85 | DHFR (0.32) | DHFRTYMSFPGS | |
| SCHEMBL30492188 | 0.85 | DHFR (0.32) | DHFRTYMSFPGS | |
| SCHEMBL25730725 | 0.85 | DHFR (0.32) | DHFRTYMSFPGS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |