Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24343413 | 0.93 | TYMS (0.33) | TYMS | |
| SCHEMBL24343465 | 0.86 | DHFR (0.34) | — | |
| SCHEMBL25833187 | 0.85 | DHFR (0.33) | TYMS | |
| SCHEMBL25833360 | 0.83 | DHFR (0.32) | TYMS | |
| SCHEMBL25725131 | 0.83 | FOLH1 (0.33) | — | |
| SCHEMBL25725100 | 0.83 | FPGS (0.32) | — | |
| SCHEMBL24343468 | 0.82 | DHFR (0.33) | TYMS | |
| SCHEMBL25837520 | 0.82 | DHFR (0.39) | — | |
| SCHEMBL25725125 | 0.80 | TYMS (0.41) | TYMS | |
| SCHEMBL24343434 | 0.80 | TYMS (0.39) | TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |