Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045813 | 0.93 | PTGS1 (0.45) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL8636154 | 0.86 | MEN1 (0.53) | MEN1POLBMAPTKMT2APTGS1 | |
| SCHEMBL8080450 | 0.83 | HTT (0.41) | TSHR | |
| SCHEMBL24141070 | 0.83 | MMP12 (0.53) | MME | |
| SCHEMBL9176049 | 0.81 | PTGS1 (0.50) | PTGS1PTGS2LMNACYP2C9AKR1C3 | |
| SCHEMBL14672109 | 0.81 | MAOB (0.53) | MEN1POLBMAPTKMT2APTGS1 | |
| SCHEMBL25146502 | 0.81 | MAOB (0.55) | HTR2A | |
| SCHEMBL28856310 | 0.81 | ESR1 (0.52) | MEN1KMT2APTGS2LMNAESR1 | |
| SCHEMBL23319649 | 0.79 | MEN1 (0.53) | MEN1POLBMAPTKMT2APTGS1 | |
| SCHEMBL18494070 | 0.78 | TAAR1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702500-B2 | Biomedical devices | BAUSCH + LOMB IRELAND LIMITED (IE) | 2023-07-18 | — | — | US | disclosed |