Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | ABL1 | P00519 | 10/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.48 |
| ▸ | KCNK4 | Q9NYG8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25260232 | 1.00 | ALDH1A1 (0.68) | ALDH1A1ABL1NPC1RAB9APIK3CG | |
| SCHEMBL30450724 | 1.00 | ALDH1A1 (0.68) | ALDH1A1ABL1NPC1RAB9APIK3CG | |
| SCHEMBL30450796 | 0.91 | ALDH1A1 (0.74) | ALDH1A1NPC1RAB9APOLBCASP6 | |
| SCHEMBL25260244 | 0.91 | ALDH1A1 (0.74) | ALDH1A1NPC1RAB9APOLBCASP6 | |
| SCHEMBL25832624 | 0.91 | ALDH1A1 (0.74) | ALDH1A1NPC1RAB9APOLBCASP6 | |
| SCHEMBL25259451 | 0.90 | ALDH1A1 (0.66) | ALDH1A1ABL1NPC1RAB9APIK3CG | |
| SCHEMBL30450121 | 0.90 | ALDH1A1 (0.66) | ALDH1A1ABL1PIK3CGITKKIT | |
| SCHEMBL25306737 | 0.90 | ALDH1A1 (0.66) | ALDH1A1ABL1PIK3CGITKKIT | |
| SCHEMBL30450168 | 0.90 | ALDH1A1 (0.66) | ALDH1A1ABL1NPC1RAB9APIK3CG | |
| SCHEMBL25833484 | 0.90 | ALDH1A1 (0.66) | ALDH1A1ABL1NPC1RAB9APIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |