Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 7/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25259451 | 1.00 | ALDH1A1 (0.66) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL30450168 | 1.00 | ALDH1A1 (0.66) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL30450710 | 0.91 | ALDH1A1 (0.70) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL25300046 | 0.91 | ALDH1A1 (0.70) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL31114419 | 0.91 | ALDH1A1 (0.64) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL25426168 | 0.91 | ALDH1A1 (0.64) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL25833491 | 0.91 | ALDH1A1 (0.64) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL25260232 | 0.90 | ALDH1A1 (0.68) | ALDH1A1ABL1PIK3CGITKMEN1 | |
| SCHEMBL30450724 | 0.90 | ALDH1A1 (0.68) | ALDH1A1ABL1PIK3CGITKMEN1 | |
| SCHEMBL25306737 | 0.90 | ALDH1A1 (0.66) | ALDH1A1ABL1PIK3CGITKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |