Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CASP3 | P42574 | 6/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 6/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 6/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 6/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CLK1 | P49759 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30450710 | 1.00 | ALDH1A1 (0.70) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL30450168 | 0.91 | ALDH1A1 (0.66) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL25833484 | 0.91 | ALDH1A1 (0.66) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL25259451 | 0.91 | ALDH1A1 (0.66) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL25303826 | 0.87 | ALDH1A1 (0.72) | ALDH1A1DYRK1ANPC1RAB9ATDP1 | |
| SCHEMBL25833395 | 0.87 | ALDH1A1 (0.72) | ALDH1A1DYRK1ANPC1RAB9ATDP1 | |
| SCHEMBL25300443 | 0.86 | ALDH1A1 (0.70) | ALDH1A1DYRK1ACYP2C19KMT2ANPC1 | |
| SCHEMBL25299185 | 0.86 | ALDH1A1 (0.70) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL30451111 | 0.86 | ALDH1A1 (0.70) | ALDH1A1DYRK1ACYP2C19KMT2ANPC1 | |
| SCHEMBL25260244 | 0.86 | ALDH1A1 (0.74) | ALDH1A1DYRK1AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INST NAT SANTE RECH MED (FR) | 2025-12-18 | — | — | US | claimed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | claimed |
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INST NAT SANTE RECH MED (FR) | 2025-12-18 | — | — | US | disclosed |
| WO-2023131649-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382273-A1 | BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS | BBOX1, NDUFB6, NDUFB5 | ALDH1A1 108/4885CASP3 2385/4885SENP8 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.